Prof. Dr. med. Daniel Simmen

Specialist (FMH) for ear, nose and throat diseases, head and neck surgery

Languages spoken

German, English, French, Italian

Core expertise

Endoscopic paranasal sinus surgery, especially frontal sinus surgery

Endoscopic skull base surgery

Rhino-neurosurgery (working together with the neurosurgeon Prof. Reisch)

Functional and reconstructive surgery of the nose

Facial plastic surgery

Reconstructive atresial ear surgery (working together with the Swiss atresia center, Cantonal Hospital Luzern, Prof. Linder)

Curriculum vitae

Since 2006

Faculty of Medicine, University of Zurich, titular professor

Since 2000

ORL-Zentrum [Center for Otorhinolaryngology, Head and Neck Surgery], Hirslanden Clinic Zurich, practicing physician

1999

Venia Legendi [highest academic degree obtainable]; lecturer for otorhinolaryngology, neck and facial surgery

1997

ORL Clinic, University Hospital Zurich, director of the department of rhinology and facial plastic surgery and senior physician

1992

ORL Clinic, University Hospital Zurich, department of rhinology and facial plastic surgery, head physician

Since 1991

Faculty of Medicine, University of Zurich, lecturer in otorhinolaryngology

1991

ORL Clinic, Cantonal Hospital St. Gallen, resident, specialized training in otorhinolaryngology

1989 – 1990

ORL Clinic, City Hospital Triemli, Zurich, resident, specialized training in otorhinolaryngology

1988 – 1989

ORL Clinic, University Hospital Zurich, resident, specialized training in otorhinolaryngology

1986 – 1988 General Surgery, City Hospital Waid, Zurich, resident in surgical training
1986 State Medical Examinations, Faculty of Medicine, University of Zurich

Publications

  1. Lesser TH, Dort JC, Simmen DP. Ear, nose and throat manifestation of Lyme disease. J Laryngol Otol. 1990 Apr; 104(4): 301-304.
  2. Wolfensberger M, Simmen D. Staple closure of the hypopharynx after diverticulectomy and total laryngectomy. Dysphagia. 1991; 6(1): 26-29.
  3. Maranta CA, Scherrer JL, Simmen D. The mask: style and volume do not influence rhinomanometry. Rhinology. 1995 Jun; 33(2): 84-85.
  4. Simmen D. Sinusitis, neue diagnostische und therapeutische Möglichkeiten. Ther Umsch. 1995 Nov; 52(11): 744-748.
  5. Kistler A, Mariauzouls C, Kuhr C, et al. Acute sympathetic responses elicited by acupuncture are pain-related and non-specific. Forsch Komplementärmed. 1996; 3: 269-278.
  6. Schuknecht B, Simmen D, Wichmann W, Valavanis A. MR identification of cavernous carotid artery involvement in septic cavernous sinus thrombosis.  Int. J. Neuroradiol. 1996 May/Jun; 2(3): 290-295.
  7. Kistler A, Huber M, Suter B, Mariauzouls C, Simmen D. A probe holder for precise intranasal microcirculation measurments. Rhinology. 1996 Jun; 34(2): 83-85.
  8. Maranta CA, Simmen D. Abschwellende Nasensprays. Ergebnisse einer rhinomanometrisch objektivierten, doppelblind durchgeführten Studie. Schweiz Med Wochenschr. 1996 Nov 2; 126(44): 1875-80.
  9. Simmen D, Schuknecht B. Computertomographie der Nasennebenhöhlen – eine präoperative Checkliste [Computerized tomography of paranasal sinuses--a preoperative checklist]. Laryngorhinootologie. 1997 Jan; 76(1): 8-13.
  10. Simmen D. Endonasale, mikroskopisch kontrollierte Stirnhöhlenchirurgie [Endonasal, microscopically controlled frontal sinus surgery]. Laryngorhinootologie. 1997 Mar; 76(3): 131-136.
  11. Simmen D, Bischoff T, Schuknecht B. Erfahrungen mit der Abklärung von Frontobasisdefekten, ein diagnostisches Konzept [Experiences with the assessment of frontobasal defects, a diagnostic concept]. Laryngorhinootologie. 1997 Oct; 76(10): 583-587.
  12. Linder TE, Simmen D, Stool SE. Revolutionary inventions in the 20th century: The history of endoscopy. Arch Otolaryngol Head Neck Surg. 1997 Nov; 123(11): 1161-63.
  13. Simmen D, Heinz B. Epistaxis - Strategie. Erfahrungen der letzten 360 Hospitalisationen [Epistaxis strategy--experiences with the last 360 hospitalizations]. Laryngorhinootologie. 1998 Feb; 77(2): 100-106.
  14. Schuknecht B, Simmen D, Yüksel C, Valavanis A. Tributary venosinus occlusion and septic cavernous sinus thrombosis: CT and MR findings. AJNR Am J Neuroradiol. 1998 Apr; 19(4): 617-626.
  15. Simmen D, Bischoff T. Rhinochirurgisches Konzept zur Versorgung von Frontobasisdefekten mit Rhinoliquorrhoe [Rhinosurgical concept in the management of fronto-basal defects with cerebrospinal rhinorrhea]. Laryngorhinootologie. 1998 May; 77(5): 264-271.
  16. Simmen D. Nasenfrakturen - Indikationen zur offenen Repositionen [Nasal fractures--indicators for open repositioning]. Laryngorhinootologie. 1998 Jul; 77(7):  388-393.
  17. Simmen D, Briner HR, Schär G, Schuknecht B. Chronische Mykosen der Nasennebenhöhlen - Stellenwert der endonasalen Nasennebenhöhlenchirurgie [Chronic mycoses of the paranasal sinuses--value of endonasal paranasal sinus surgery]. Laryngorhinootologie. 1998 Aug; 77(8): 444-453.
  18. Simmen D, Briner HR, Hess K. Screeningtest des Geruchssinnes mit Riechdisketten [Screening of olfaction with smell diskettes]. Laryngorhinootologie. 1999 Mar; 78(3): 125-130.
  19. Simmen D, Scherrer JL, Moe K, Heinz B. A dynamic and direct visualization model for the study of nasal airflow. Arch Otolaryngol Head Neck Surg. 1999 Sep; 125(9):
     015-1021.
  20. Briner HR, Simmen D. Smell diskettes as screening test of olfaction. Rhinology. 1999 Dec; 37: 145-148.
  21. Schmidt MC, Simmen D, Hilbe M et al. Validation of excised bovine nasal mucosa as in vitro model to study drug transport and metabolic pathways in nasal epithelium. J Pharm Sci. 2000 Mar; 8(3): 397-407.
  22. Kraft M, Simmen D, Schmid S, Casas R, Pfaltz M. Significance of human papilloma viruses (HPV) in sinonasal papillomas. Schweiz Med Wochenschr Suppl. 2000; 116: 113S-115S. In German.
  23. Simmen D. Progress in endonasal microsurgery of the paranasal sinuses. Laryngorhinootologie. 2000 Nov; 79(11): 645-647. In German.
  24. Kraft M, Simmen D, Casas R, Pfaltz M. Significance of human papilloma viruses in sinonasal papillomas. J Laryngol Otol. 2001 Sep; 115(9): 709-714.
  25. Hofbauer GF, Böni R, Simmen D et al.  Histological, immunological and molecular features of a nasal mucosa primary melanoma associated with nasal melanosis. Melanoma Res. 2002 Feb; 12(1): 77-82.
  26. Schuknecht B, Simmen D. State of the art. Diagnostic imaging of paranasal sinus diseases. Laryngorhinootologie. 2002 Feb; 81(2): 126-146. In German.
  27. Briner HR, Simmen D, Jones, N. Impaired sense of smell in patients with nasal surgery. Clin Otolaryngol Allied Sci. 2003 Oct; 28(5): 417-419.
  28. Kraft M, Simmen D, Kaufmann T, Holzmann D. Long-term results of endonasal sinus surgery in sinonasal papillomas. Laryngoscope. 2003 Sep; 113(9): 1541-1547.
  29. Holzmann D, Speich R, Kaufmann T et al. Effects of sinus surgery in patients with cystic fibrosis after lung transplantation: a 10-year experience. Transplantation. 2004 Jan 15; 77(1): 134-136.
  30. Spörri S, Simmen D, Briner HR, Jones N. Objective assessment of tip projection and the nasolabial angle in rhinoplasty. Arch Facial Plast Surg. 2004 Sep-Oct; 6(5): 295-298; discussion 299-300.
  31. Simmen D, Jones, N. Manual of Endoscopic Sinus Surgery and its Extended Applications. Stuttgart: Thieme; 2005 (300 pages, 998 illustrations, DVD; received the George Davies Howells Memorial Prize 2006 in otolaryngology of the University of London).
  32. Simmen D, Jones, N. Chirurgie der Nasennebenhöhlen und der vorderen Schädelbasis. Stuttgart: Thieme; 2005. (298 pages, 998 illustrations, DVD)
  33. Briner HR, Simmen D, Jones N. Endoscopic sinus surgery: advantages of the bimanual technique. Am J Rhinol. 2005 May-Jun; 19(3): 269-273.
  34. Simmen D, Briner HR. Olfaction in rhinology – methods of assessing the sense of smell. Rhinology. 2006 Jun; 44(2): 98-101.
  35. Simmen D, Raghavan U, Briner HR, et al. The surgeon’s view of the anterior ethmoid artery. Clin Otolaryngol. 2006 Jun; 31(3): 187-191.
  36. Simmen D, Raghavan U., Briner HR, et al. The anatomy of the sphenopalatine artery for the endoscopic sinus surgeon.  Am J Rhinol. 2006 Sep-Oct; 20(5): 502-505, 2006.
  37. Treyer V, Koch H, Briner HR, Jones NS, Buck A, Simmen DB. Male subjects who could not perceive the pheromone 5a-androst-16-en-3-one, produced similar orbitofrontal changes on PET compared with perceptible phenylethyl alcohol (rose). Rhinology. 2006 Dec; 44(4): 278-282.
  38. Broglie M, Holzmann D, Simmen D, Studer G, Tinguely M, Stöckli S. Aesthesioneuroblastom der NNH – Erfahrungen an der ORL-Klinik des Universitätsspitals Zürich von 1983 bis 2004. Schweiz Med Forum. 2007; 104S-107S. 
  39. Briner HR, Simmen D. Therapie von Tumoren der Nasennebenhöhlen und der anterioren Schädelbasis mit der bimanuellen endoskopischen Technik. Schweiz Med Forum. 2007 (Suppl. 34); 108S-110S.
  40. Briner HR, Simmen D, Jones N, et al. Evaluation of an anatomic model of the paranasal sinuses for endonasal surgical training. Rhinology. 2007 Mar; 45(1): 20-23.
  41. Schuknecht B, Simmen D, Briner HR, Holzmann D: Nontraumatic skull base defects with spontaneous CSF rhinorrhea and arachnoid herniation: imaging findings and correlation with endoscopic sinus surgery in 27 patients.  AJNR Am J Neuroradiol. 2008 Mar; 29(3): 542-549.
  42. Simmen D. Medical and surgical treatment options in the management of upper airway diseases. Ther Umsch. 2008 Mar; 65(3):175-80. In German.
  43. Briner HR, Hammer B, Kirsch E, et al. Transnasaler endoskopischer Zugang zur anterioren Schädelbasis. Schweiz Med Forum. 2009 (Suppl. 49): 51S-53S.
  44. Eichenberger A, Simmen D, Briner HR, Caversaccio M-D. Erste Erfahrungen mit der Ballonsinuplastie bei chronischer Rhinosinusitis der Nasennebenhöhlen. Schweiz Med Forum. 2009 (Suppl. 49): 57S-59S.
  45. Simmen D. Technical advances and the endoscopically assisted bimanual technique (Chapter 4: 38-45); Endonasal surgery of the anterior skull base (Chapter 8: 73-82); Sinus surgery and olfaction in chronic rhinosinusitis (Chapter 17: 150-158). In: Jones, N. Practical Rhinology. Boca Raton, FL: CRC Press; 2010 (book chapters).
  46. Simmen D, Jones N. Epistaxis. In: Flint P et al. eds., Cummings Otolaryngology--Head & Neck Surgery, 5th ed.  Philadelphia: Mosby Elsevier; 2010: 682-693 (book chapter).
  47. Simmen D, Jones N. Olfaction and Nasal Polyposis. In: Fergusson B, Onerci M.  Nasal Polyposis. Berlin/Heidelberg: Springer; 2010: 163-173 (book chapter).
  48. Dhanasekar G, Simmen D, Briner HR. Breathing straws. J Laryngol Otol. 2010 Jan; 124(1): 73-74.
  49. Lund VJ, Stammberger H, Nicolai P et. al. European position paper on endoscopic management of tumours of the nose, paranasal sinuses and skull base. Rhinol Suppl. 2010 Jun 1; (22): 1-143.
  50. Simmen D, Briner HR, Jones N. Endoscopically assisted bimanual technique. In: Stamm AC, ed. Transnasal Endoscopic Skull Base and Brain Surgery: Tips and Pearls. New York/Stuttgart: Thieme; 2011: 92-98 (book chapter).
  51. Heimgartner S, Eckardt J, Simmen D, Briner HR, Leunig A, Caversaccio M-D. Limitations of balloon sinuplasty in frontal sinus surgery.  Eur Arch Otorhinolaryngol. 2011 Oct;  268(10): 1463-1467.
  52. Briner HR, Jones N, Simmen D. Olfaction after sinus surgery: long-term results. Rhinology. 2012 Jun; 50(2): 178-184.
  53. Braun T, Betz CS, Ledderose GJ, et al. Endoscopic sinus surgery training courses: benefit and problems – a multicentre evaluation to systematically improve surgical training. Rhinology. 2012 Sep; 50(3): 246-254.
  54. Simmen D, Jones N. A Manual of Endoscopic Sinus and Skull Base Surgery. Stuttgart: Thieme; 2013 (450 pages, 1500 illustrations, DVD).
  55. Landis BN, Briner HR, Lacroix JS, Simmen D. Olfaction and Its Disorders. In: Georgalas C, Fokkens W, eds. Rhinology and Skull Base Surgery. From the Lab to the Operating Room: An Evidence-based Approach. New York/Stuttgart: Thieme; 2013: 195-210 (book chapter).
  56. Simmen D, Jones N. Epistaxis. In: Flint P et al. eds., Cummings Otolaryngology--Head & Neck Surgery, 5th ed.  Philadelphia: Mosby Elsevier; 2013: Chapter 48.
  57. Simmen D, Jones N. Patient selection. Laryngorhinootologie. 2013 Aug; 92(8): 565-572. In German.
  58. Simmen D, Jones N. Patient expectations - optimizing diagnosis, medical management and planning the operation - optimizing diagnosis- 2. Laryngorhinootologie. 2013 Sep; 92(9): 623-633. In German.
  59. Simmen D, Jones N. Optimizing diagnosis, medical management and planning of surgery - optimizing diagnosis - II. Laryngorhinootologie. 2013 Oct; 92(10): 708-712. In German.
  60. Simmen D, Jones N. Optimizing diagnosis, medical management and planning of surgery. Optimizing drug therapy. Optimizing operation timing. Laryngorhinootologie. 2013 Nov; 92(11): 779-785. In German.
  61. Simmen D, Jones N. Symptom related, realistic goals of surgical interventions in patients with rhinosinusitis. Laryngorhinootologie. 2013 Dec; 92(12): 857-865. In German.
  62. Lund VJ, Stammberger H, Fokkens WJ et al. European position paper on the anatomical terminology of the internal nose and paranasal sinuses. Rhinol Suppl. 2014 Mar; (24): 1-34.
  63. Simmen D, Jones N. Sphenoethmoidektomie ± sphenoidal Sinusotomie Typ I, II, III – Teil 1.  Laryngorhinootologie. 2014 Jun; 93(6): 423-429. In German.
  64. Simmen D, Jones N. Management der mittleren und oberen Nasenmuschel.  Laryngorhinootologie. 2014 Jul; 93(7): 487-492. In German.
  65. Koechlin NO, Simmen D, Briner HR, Reisch R. Combined transnasal and transcranial removal of a giant clival chordoma. J Neurol Surg Rep. 2014 Aug; 75(1): e98-e102.
  66. Simmen D, Jones N. Die endoskopische Untersuchung, anatomische Varianten und besondere Umstände [The endoscopic examination, anatomical variants and special circumstances]. Laryngorhinootologie. 2014 Aug; 93(8): 573-577. In German.
  67. Simmen D, Jones N, Briner HR.  Preserving and Improving the Sense of Smell. In: Simmen D, Jones N.  A Manual of Endoscopic Sinus and Skull Base Surgery. New York/Stuttgart: Thieme; 2014; 60-66 (book chapter).
  68. Simmen D, Jones N, Briner HR.  Applied Anatomy for Endoscopic Sinus and Skull Base Surgery. In: Simmen D, Jones N.  A Manual of Endoscopic Sinus and Skull Base Surgery. New York/Stuttgart: Thieme; 2014; 80-90 (book chapter).
  69. Koechlin NO, Briner HR, Simmen D, Reisch R. Fortschritte in der chirurgischen Behandlung von Tumoren der Hypophysenregion [Advances in the surgical treatment of tumors of the pituitary region: rhino-neurosurgical transnasal endoscopic surgery]. HNO. 2014 Nov; 62(11): 793-799, 2014.  In German.
  70. Daniel B. Simmen. Extended Frontal Sinusotomy – Draf III or Median Drainage Procedure. In: Myers E.N., Kennedy D.W., eds. Mater Techniques in Otolaryngology – Head and Neck Surgery, Rhinology: New York, London, Tokyo: Wolters Kluwer;  2015: 153-164 (book chapter).
  71. Stefania Gallo, Sarah Grossi, Giulia Montrasio, Giorgio Binelli, Raffaella Cinquetti, Daniel Simmen, Paolo Castelnuovo and Paola Campomenosi. TAS2R38 taste receptor gene and chronic rhinosinusitis: new data from an Italian population.
  72. Sommer F, Simmen D, Briner HR, Jones N, Hoffmann TK, Lindenmann J. Effects of nasal wall lateralisation and pyriform turbinoplasty on nasal air conditioning. Otolaryngol Head Neck Surg 2016 doi: 10.15761/OHNS.100135. Vol 2(1) 1-5.
  73. Eördögh M, Briner HR, Simmen D, Jones N, Reisch R. Endoscopic unilateral transethmoidal-paraseptal approach to the central skull base. Laryngoscope Investigative Otolaryngology 2017 May; doi: 10.1002/lio2.82.
  74. Simmen D, Narendrankumar V, Briner HR, Jones N, Schuknecht B. Anterior maxillary wall and lacrimal duct relationship – CT analysis for prelacrimal access to the maxillary sinus. Rhinology 2017 Jun; 55(2): 170-174.

National and international congresses and practical operations courses

Active participation (lectures, roundtable discussions, live operations) in the fields of rhinology, skull base surgery and facial plastic surgery

Participation in congresses and practical courses

Active participation (lectures, live dissections and operations) in the fields of rhinology, skull base surgery and facial plastic surgery

Membership in professional associations

Swiss Society of Oto-Rhino-Laryngology, Head and Neck Surgery

German Society of Oto-Rhino-Laryngology, Head and Neck Surgery

Société Suisse Romande de Rhinologie (SSRR)

European Rhinologic Society

International Rhinologic Society

European Academy of Pediatric Otorhinolaryngology

European Academy for Facial Plastic Surgery

American Academy for Facial Plastic and Reconstructive Surgery

Austrian Society of Otorhinolaryngology, Head and Neck Surgery, honorary member (since 2009)

Polish Rhinological Society, honorary member (since 2010)

German HNO Society, corresponding member (2010)

South African Society for Otorhinolaryngology, Head and Neck Surgery, honorary member (since 2011)

ARTIFFEX RHINOLOGIAE Polish Rhinological Society, Honorary Member

YEARSLEY LECTURE, BACO, Liverpoo